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Traumatic Brain Injury Research

Traumatic brain injury (TBI) research at Kessler Foundation explores potential treatments and interventions for deficits in cognition, mobility, and emotional processing.

Examining Cognitive and Physical Fatigue in Traumatic Brain Injury

This study examines brain and behavioral changes during thinking and physical tasks in individuals with TBI. Participants perform exercise tests using an exercise bike, receive two magnetic resonance imaging (MRI) scans, and complete tests of thinking skills and questionnaires.

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Well-being Interventions for Adults with Traumatic Brain Injury

This study evaluates the effectiveness of two interventions to improve well-being in adults with TBI.

All sessions are completed via an online platform such as Zoom. This study does not require in-person visits.

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The Effects of Effort on Fatigue and Brain Activity in TBI

This study examines how patterns of brain activity relate to cognitive fatigue, which is a feeling of exhaustion and inability to perform thinking-related activities.

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Comparing the Effectiveness of Upper Limb Tele-rehab and an Exercise Video Game in People with TBI

This study compares the effectiveness of an exercise video game (Exergame) and a home-based arm and hand exercise (HAHE) program to improve daily functions and quality of life in people with brain injuries who have impairments in the use of their arms and hands.

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Applying Exercise to Improve Cognition in TBI

This study compares the effects of two, 12-week exercise programs (aerobic cycling or stretching-and-toning) combined with memory retraining on cognitive (thinking) performance in people with traumatic brain injury (TBI).

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Workforce Skills for Young People with TBI

Study aims to improve work readiness by focusing on social skills. Participants enroll in a fully remote, 15-week training program designed to enhance social interaction and address employment needs of transition-age youth and young adults with TBI.

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Comparison of Two Different Group Wellness Programs for People with TBI and their Support Persons

This study compares the effect of two different types of group wellness treatments for individuals with moderate or severe traumatic brain injury (TBI) and their support persons.

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A Virtual Reality Oculomotor Exercise for Restoring Functional Vision After Head Trauma

The purpose of the study is to better understand the brain mechanisms of visual problems after a traumatic brain injury. The study will involve completing online surveys, paper-based assessments, and a virtual reality session. Some participants will be selected for an MRI scan.

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Feedback and Learning in Individuals with Clinical Depression and TBI

The purpose of this research study is to examine the influence of 'feedback timing' (feedback about your performance is either presented immediately or after a delay) on learning and brain function in individuals with moderate to severe TBI with or without depression. 


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Improving Walking Using Virtual Reality-based (VR) Treadmill Training in TBI

The purpose of this study is to test the effectiveness of VR-based treadmill training on walking ability. Researchers are also examining changes in thinking ability and brain activity as a result of the VR-based treadmill training.

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Using Virtual Reality to Improve Job Reentry in Adults with TBI

This study investigates the effectiveness of virtual reality (VR) to improve job reentry skills in individuals with TBI. 

This study is completely remote and does not require in-person visits.

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Improving Postural Responses to Avoid Falls after TBI

The purpose of this study is to assess a balance training program to see if it can be helpful in avoiding falls in people with TBI. 

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Northern New Jersey TBI Model Systems

The purpose of this study is to provide information which may help improve the treatment, care, and outcomes of people with traumatic brain injury (TBI).

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