spinal cord injury research

Comparing Drug Treatments for Neurogenic Detrusor Overactivity in SCI

The purpose of this study is to determine the effectiveness and safety of "Mirabegron" compared to "Oxybutynin IR" for a condition called neurogenic detrusor overactivity in individuals with SCI . Neurogenic detrusor overactivity is common in people with SCI and is a medical condition characterized by involuntary urinary bladder contractions. 

Actively Recruiting

Approximately 4 months, including 8 visits, with an additional follow-up visit at the end if needed. 

Inclusion Criteria
  • Individuals aged 18-70 years. 
  • Have limited mobility because of an SCI that occurred at least 12 months prior to the screening visit.
  • Level of injury is above T12.
  • Method of bladder management is intermittent catheterization or indwelling catheter. 
  • Have documented neurogenic detrusor overactivity, as determined by a study physician. 
  • Currently taking oxybutynin or have been told I should take oxybutynin. 

Up to $800 for completing the study. 

IRB Number:


Research Coordinator