MS Research at Kessler Foundation

Biomarker for Cognitive Fatigue in MS Using fMRI

The purpose of this research is to investigate the effectiveness of Tysabri (Natalizumab) on cognitive fatigue in people with relapsing remitting multiple sclerosis (RRMS). 

Note*** Participants with RRMS must be patients at RWJ Barnabas Health.

Actively Recruiting
Yes
Duration

Participation lasts approximately 6 months. To determine eligibility, participants complete a screening visit lasting approximately 20 minutes. Once enrolled, participants complete two sessions:

Session 1: fMRI session (75 minutes) followed by paper and pencil tests (3 hours). This session can be split up into two separate visits if needed. 

Session 2: 6 month follow-up fMRI session (75 minutes) followed by paper and pencil tests (3 hours). Participants may be asked to complete questionnaires prior to this visit. 

Inclusion Criteria
  • Individuals diagnosed with RRMS who have been prescribed Tysabri by their medical doctor
  • 18-64 years of age
  • speak and read English fluently

Or

  • healthy volunteers 
  • 18-64 years of age
  • speak and read English fluently.
Compensation

Participants who complete the study receive up to $200. 

Research Categories
Healthy Volunteers
Multiple Sclerosis
IRB Number:

R-1094-20

Research Coordinator