Understanding the Trajectory of MS

Our researchers use advanced methods, including neuroimaging, exercise science, robotics, and behavioral science, to study how MS affects people over time. This work explains how MS-related changes impact daily life and helps shape rehabilitation at different stages of the disease.

Interventions to Enhance Everyday Function

Implementing Exoskeleton-Assisted Exercise

Robotic exoskeletons are promising interventions to address the mobility and cognitive impairments that are associated with MS. Research by scientists like Ghaith J. Androwis, PhD, aims to increase capacity to move and perform daily activities for people with MS. 

Using MRI to Study MS

Through earlier discoveries, Kessler Foundation scientists like Glenn Wylie, DPhil  used MRI to identify a biomarker that now helps shape new studies aimed at improving treatment for MS. They've also learned that exercise helps recover lost functions for people with relapse-remitting and progressive MS.

The Power of Social Connections

Kessler Foundation researchers like Lauren Strober, PhD, are exploring how social bonds, coping skills, and behavioral therapies enhance well-being for people with multiple sclerosis. Strong friendships, especially among women, may reduce fatigue, pain, and depression while boosting well-being and resilience. 

Our Scientists Studying Multiple Sclerosis
Improving Memory and Well-Being in MS
Female Medical Doctor explaining scan results to patient
Developing Strategies to Improve Memory

New learning, memory, and processing-speed deficits, common in MS, negatively impact everyday life. Two established cognitive rehabilitation protocols developed by Nancy Chiaravalloti, PhD, and supported by Class I research evidence, target specific cognitive functions and enhance the ability for individuals with MS to learn and remember. The two protocols are: Kessler Foundation Strategy-based Training to Enhance Memory (KF-STEM) and Kessler Foundation modified Story Memory Technique (KF-mSMT®)

Woman on treadmill exercises while male researcher in business suit observes standing next to the machine.
Enhancing Cognition Through Exercise

Foundation researcher Brian M. Sandroff, PhD, has accumulated strong evidence to support the use of physical exercise training, such as treadmill walking, cycling, and outdoor walking, to effectively restore functions that have been lost due to MS. Studies involve focusing on individual and synergistic effects of cognitive rehabilitation and exercise in individuals with relapsing-remitting and progressive MS.

Several people of different ethnicities sit together having a group discussion.
Studying Quality of Life and Outcomes

Disease- and person-specific secondary factors from MS, such as depression, sleep disturbance, and personality changes, place significant demands on individuals’ ability to manage the illness and live fulfilling lives. Lauren Strober, PhD, researches psychosocial interventions targeting MS symptoms and occupational outcomes aimed at advancing self-efficacy, coping, and well-being through behavioral therapy and positive psychology technique

Woman views a computer screen that shows a red dot in the center as point of reference.
Relating Eye Movements and Processing-Speed Deficits

Although the visual symptoms associated with MS are well-documented, their impact has received limited attention. To address this issue, reacher Silvana Lopes Costa, PhD, is studying the link between eye movements and processing-speed deficits in MS and developing protocols for assessing cognitive function using eye trackers, irrespective of an individual’s motor abilities.

 
 

 
Our Specialized Centers Dedicated to MS Rehabilitation

Your Support Drives Change

When you give to Kessler Foundation, you make a difference in the quality of life for people with multiple sclerosis. 

Therese Bertrand in her craft room

Therese Bertrand, Finding My Way Forward With Multiple Sclerosis

A phone call changed Therese Bertrand's life. It brought a diagnosis she had never expected...

Read More
Person standing at a bowling lane holding a blue bowling ball, with polished lanes and pins visible in the background.

Beth Holcomb Is Back on the Ball with MS

Beth Holcomb has lived with multiple sclerosis for nearly twenty years. “Symptoms come and go, but fatigue remains,” explains Beth...

Read More
A woman in an outdoor setting using a walker for mobility support

Carla Basante Adapts and Gives Back After MS

Carla Basante lives with multiple sclerosis and has been a longtime participant in Kessler Foundation research...

Read More
Read MileStones, Our MS Newsletter
Image
Milestones - Spring 2026 Newsletter: Evolution or Revolution?
April 16, 2026
Image
Milestones - Fall 2025: Early Changes, Everyday Impact
October 10, 2025
Image
Milestones - Winter 2024/25: Exercising the brain
May 20, 2025
Image
Milestones - Spring 2024: Keeping an Eye Out
May 10, 2024

Our Multiple Sclerosis Scientists in Action

Pilar Moves Forward Without a Wheelchair
Pilar Moves Forward Without a Wheelchair
Celebrating International Day of Women and Girls in Science
Celebrating International Day of Women and Girls in Science
Lessons in Leadership: Brian Sandroff, PhD, Kessler Foundation
Lessons in Leadership: Brian Sandroff, PhD, Kessler Foundation
What Can People With MS Do to Improve Cognition?
What Can People With MS Do to Improve Cognition?
Meet Meg Balter, MS Research Participant
Meet Meg Balter, MS Research Participant