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Informing a Caregiver-Driven Vision for Future Services and Supports

This fully remote study gathers input from family caregivers of people with SCI to better understand their needs and improve future support services and resources.

Spinal Cord Transcutaneous Stimulation for Upper Extremity Function Recovery in Acute to Subacute Cervical Spinal Cord Injury

This study aims to understand the safety and practicality of providing stimulation to the spinal cord through the skin (referred to as "transcutaneous stimulation") in people who are receiving inpatient rehabilitation. The study will also determine if combining stimulation with therapy that involves the upper limbs can improve participants' ability to use their hands, arms, and trunk during inpatient treatment at Kessler Institute for Rehabilitation.

Blood Pressure Changes with Transcutaneous Spinal Stimulation in a Recently Acquired Spinal Cord Injury

This study examines the use of spinal stimulation applied through the skin (referred to as transcutaneous spinal stimulation) in treating orthostatic hypotension (a drop in blood pressure when moving from lying flat on your back to an upright position) in individuals with a recently acquired spinal cord injury, during inpatient rehabilitation.

Improving Balance Using a Robotic Upright Stand Trainer and Spinal Cord Epidural Stimulation

This study investigates how standing and sitting balance control is altered after spinal cord injury and how a new type of robotic assistive device may be used to improve muscle function.

Targeted Epidural Stimulation for Recovery of Nervous System Function, Movement, and Standing after Severe SCI

This study evaluates the effects of epidural stimulation of the spinal cord on cardiovascular (blood pressure regulation) function, voluntary movement of the legs and trunk, and standing/weight bearing in individuals with spinal cord injury.

Nerve Stimulation for Upper Extremity Recovery in Chronic Cervical Spinal Cord Injury

Study seeks to understand how the combination of upper extremity activity-based recovery training and targeted spinal cord transcutaneous (through the skin) stimulation can improve participants’ ability to use their hand, arms, and trunk.

Blood Pressure Modulation with Transcutaneous Spinal Stimulation in Chronic Spinal Cord Injury

Study examines the use of spinal stimulation applied through the skin (referred to as transcutaneous spinal stimulation) in treating orthostatic hypotension (a drop in blood pressure when moving from lying flat on your back to an upright position) in individuals with a spinal cord injury.

Extracorporeal Shockwave Therapy on Spasticity in SCI

The purpose of this study is to evaluate the effectiveness of a new treatment for spasticity called extracorporeal shockwave therapy.

Identification of New Biomarkers for Determining Risk of Lower Extremity Fracture during Exoskeleton-assisted Ambulation

The purpose of this study is to determine the forces on the hips, knees, and ankle joints while participating in exoskeleton-assisted sit-to-stand training protocol as well as exoskeleton-assisted walking (EAW) in the ReWalk, Indego, and Ekso devices.

Treatment of Bone Loss in Persons with Chronic Spinal Cord Injury

The purpose of this study is to determine the usefulness of taking Romosozumab for 1 year compared to a placebo (salt solution) followed by 1 year of Denosumab in those who had a spinal cord injury longer than 3 years. Romosozumab and Denosumab are both FDA approved drugs to treat osteoporosis (thinning and weakening of the bone) in those at risk for fracture.

Prevention of Bone Loss in Persons with Subacute Spinal Cord Injury

The purpose of this study is to compare Romosozumab for 12 months followed by Denosumab for 12 months vs. 24 months of Denosumab in persons with spinal cord injury less than 6 months prior to enrollment

Brain Activity in People with Chronic Neuropathic Pain and SCI

The purpose of this research study is to learn more about how patterns of brain activity change during different thinking tasks and how these changes relate to the intensity and unpleasantness of the neuropathic pain experienced.

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Every discovery begins with people. It’s accelerated by those who choose to take part, and donors who choose to act.

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A person seated in a power wheelchair in front of a Kessler Foundation backdrop

FAQs About Joining a Research Study

Rehabilitation research studies are designed to help people with neurological and physical conditions become as independent as possible in everyday activities, restore function and mobility, enhance memory and learning, and improve quality of life.   

First, check out our list of research studies that are now enrolling participants. Once you find a study that interests you, complete the “Join a Study” form found on each study page. Then a member of our research recruitment team will reach out to discuss the study and determine whether you are eligible to participate. 

Our scientists seek to improve memory and learning, mobility, and long-term outcomes, including employment, for people with neurological and physical disabilities including traumatic brain injury, spinal cord injury, stroke, multiple sclerosis, and autism. We also study the role of caregivers who assist individuals with disabilities with daily activities, and we help people return to the workplace after disabling illnesses or injuries. 

We offer a number of tele-studies that can be completed from your home, while others may require you to visit one of two Foundation locations in East Hanover, NJ, or West Orange, NJ. In some cases, we may be able to travel to your home or provide reimbursement for travel to our offices. 

Some studies are completed in one day, while others may need volunteers to be available for follow up from six weeks to more than a year. 

To achieve results that help as many people as possible, participants of all ages and ethnicities are needed in our studies. 

Yes, absolutely! People without disabilities can serve as controls in research studies. Comparing the results between people with and without disabilities helps researchers prove the efficacy of their interventions. 

Participating in our research studies is completely voluntary, and if at any time anyone is uncomfortable or unable to continue the study, they are able to withdraw. 

Most of our studies provide compensation to volunteers for participation. The amount paid varies for every study. Some studies reimburse participants for travel or cover Uber Health or Lyft Concierge rides. 

Each individual has their own motive for participating, but volunteers are vital to the ongoing rehabilitation research at Kessler Foundation. Their assistance helps scientists identify new treatments and interventions that can change the lives of loved ones and others with disabilities and debilitating health conditions. These scientific advances are made possible when people like you volunteer for research. To learn more, read our article “3 Reasons to Join a Research Study.” 

Complete Our Join a Study Form

Tell us a little more about yourself so that our recruitment team can help you enroll in a study that is right for you.

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