Our research contributes to accelerating recovery following acquired brain injury, spinal cord injury, and multiple sclerosis by guiding new rehabilitation approaches informed by a better understanding of the underpinnings of neuroplasticity, functional adaptation to injury, and exoskeleton-based robotic interventions.
Guang Yue, PhD, is acting director of the Advanced Rehabilitation Neuroimaging Laboratory within Kessler Foundation's Center for Mobility and Rehabilitation Engineering Research, where he is director. Lab researchers investigate the underlying mechanisms of neuromuscular function across several areas, including neural networks involved in motor control; neuroplasticity following acquired brain injury, spinal cord injury, and multiple sclerosis; and responses to rehabilitation interventions. To better understand disease, injury, and rehabilitation-related recovery mechanisms, the Lab team applies cutting-edge neuroimaging techniques to perform these investigations in individuals with motor disabilities.
The team initiated the first investigations into the cortical control of walking with and without exoskeleton-assisted walking and conducted a comprehensive study to evaluate a progressive, adaptive, assist-as-needed, intensive exoskeleton robotic intervention, including 30 hours of training, in the subacute phase post-stroke. Ongoing studies report on the intervention’s effect on functional recovery, neuromuscular adaptations, and neuroplasticity. The ultimate goal is to improve function and quality of life for individuals with motor disabilities.
National Institutes of Health
New Jersey Commission on Spinal Cord Research
