spinal cord injury research

Cortical Control of Walking: Brain Plasticity Following Exoskeleton Training in Incomplete Spinal Cord Injury (iSCI)

In this pilot study, we want to study the neural mechanism of walking in able-bodied subjects and iSCI subjects who have some control of muscles below the level of injury (American Spinal Injury Association Impairment Scale (AIS) D).
Actively Recruiting
Yes
Duration

One session of 2-3 hours if able -bodied or an iSCI participant not enrolled in training intervention.

If iSCI participant enrolled in exoskeleton-assisted gait training intervention, 3 testing sessions of 3-4 hours before training, and after 20 and 40 hours of training. 

Inclusion Criteria

If able bodied:

  • Able to give informed consent.
  • 18-50 years old.
  • Have no physical, neurological or cognitive impairment and able to hold crutches. 
  • Be of height between 5'3''-6'3''.
  • Weigh less than 220 lbs.
  • Right-handed.
  • Proficient in English.

If an iSCI subject, you will have to meet the above requirements and the following:

  • Neurological level between C6-T10, and an impairment of either C or D.
  • Medically stable at time of enrollment.
  • No history of seizures.
  • Have a low spasticity score. 
  • Have a lower extremity motor score greater than 17. 
  • Injury occurred more than 1 year but less than 2 years ago.
Compensation

$50 for each testing session.

Research Categories
Healthy Volunteers
Spinal Cord Injury
IRB Number:

R-940-16