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Cortical Control of Walking: Brain Plasticity Following Exoskeleton Training in Incomplete Spinal Cord Injury (iSCI)

In this pilot study, we want to study the neural mechanism of walking in able-bodied subjects and iSCI subjects who have some control of muscles below the level of injury (American Spinal Injury Association Impairment Scale (AIS) D).
Duration

One session of 2-3 hours if able -bodied or an iSCI participant not enrolled in training intervention.

If iSCI participant enrolled in exoskeleton-assisted gait training intervention, 3 testing sessions of 3-4 hours before training, and after 20 and 40 hours of training. 

Inclusion Criteria

If able bodied:

  • Able to give informed consent.
  • 18-50 years old.
  • Have no physical, neurological or cognitive impairment and able to hold crutches. 
  • Be of height between 5'3''-6'3''.
  • Weigh less than 220 lbs.
  • Right-handed.
  • Proficient in English.

If an iSCI subject, you will have to meet the above requirements and the following:

  • Neurological level between C6-T10, and an impairment of either C or D.
  • Medically stable at time of enrollment.
  • No history of seizures.
  • Have a low spasticity score. 
  • Have a lower extremity motor score greater than 17. 
  • Injury occurred more than 1 year but less than 2 years ago.
Compensation

$50 for each testing session.

Research Categories
Spinal Cord Injury
Healthy Volunteers
Actively Recruiting
Yes