Testosterone Replacement Therapy and Electrical Stimulation in SCI

The aim of this study is to understand what happens to muscle and bone in spinal cord injured males with low testosterone levels after 5 months of stand training with body weight support (BWS) and testosterone replacement therapy (TRT). TRT is administered in the form of a skin gel dispensed from a pump containing testosterone and by using electrical stimulation (ES).

Actively Recruiting

Study participation lasts a total of 38 weeks including: 3 weeks of pre-testing evaluations, 20 weeks of intervention training, and 3 weeks of post-evaluation. There is also a 3 month follow-up for some of the evaluation measures. 

Inclusion Criteria
  • Males aged 18-58 years.
  • Level of injury is C5-T10 and impairment grade of A, B, or C according to ASIA impairment scales. 
  • Must be wheelchair reliant for more than 75% of the time.
  • Must have low testosterone levels (350ng/dL or below) as determined by a blood test completed during the screening portion of the study. 
  • Must be able to tolerate electrical stimulation and must show visible muscle contraction to an electrical stimulus. 

$50 after every 5 sessions of training. 

IRB Number:


Research Coordinator