This study compares the effects of two, 12-week exercise programs (aerobic cycling or stretching-and-toning) combined with memory retraining on cognitive (thinking) performance in people with traumatic brain injury (TBI).
Participation lasts 3 months.
Baseline visits: Participants complete tests of thinking skills, questionnaires, and a 10-15 minute exercise test using a stationary bike (visit is approximately 3 hours). Within the next week, participants complete an MRI/fMRI scan, additional tests of thinking skills, and questionnaires (approximately 2 hours).
Intervention visits: Participants are then randomly assigned to participate in one of two groups for the next 12 weeks: An in-person aerobic cycling exercise program or an in-person stretching-and-toning exercise program. Both groups complete the same memory-retraining program.
Follow-up visits: At the end of the 12-week training program, participants complete a short-term follow-up visit and repeat the same tests done during baseline testing (approximately 3 hours). Within the next week, participants complete an MRI/fMRI scan, additional tests of thinking skills, and questionnaires (approximately 2 hours).
People with moderate-to-severe TBI who:
- Are 18-65 years old
- Sustained a TBI at least 1 year prior to enrollment
- Have problems with thinking performance
- Are right-handed
- Have corrected vision better than 20/80
- Speak English as a primary language
$350
R-1195-22
