MS Research at Kessler Foundation

Cognitive Rehabilitation and Physical Exercise in People with Progressive Multiple Sclerosis

The purpose of this research is to study whether completing thinking exercises on a computer combined with physical exercise is an effective treatment for difficulties with thinking, memory, and problem-solving in individuals with Progressive Multiple Sclerosis (PMS).

Actively Recruiting

Participation lasts approximately 9 months. Participants will complete initial baseline testing of thinking skills, physical fitness, and an optional fMRI scan. Participants are then randomly assigned to one of two training groups that meet twice a week for 12 weeks and complete short-term and long-term follow-up testing.

Inclusion Criteria
  • Individuals diagnosed with primary or secondary progressive MS
  • 25-65 years of age
  • no other neurological disorders or disease (e.g. stroke, brain injury, epilepsy)
  • do not use a wheelchair as primary mode of transit.

Participants who complete the study receive $225. Participants who qualify for the fMRI scans and decide to participate will receive an additional $75.

Research Categories
Multiple Sclerosis
IRB Number:


Research Coordinator