This study examines how brain stimulation can help improve performance in tasks that normally cause fatigue or weakness in women who have had breast cancer. This study is also enrolling healthy female volunteers who have not had breast cancer for the control group.
MRI Studies
MRI Studies on Breast Cancer
MRI Studies on Fatigue
Establishing a Clearer Measure of Mental Fatigue in Multiple Sclerosis
This study examines mental fatigue that is regularly experienced by people with multiple sclerosis. Researchers will examine levels of mental fatigue by looking at brain activation during an MRI scan and analyzing self-reported mental fatigue provided during study participation.
Examining Cognitive and Physical Fatigue in Traumatic Brain Injury
This study examines brain and behavioral changes during thinking and physical tasks in individuals with traumatic brain injury. Participants perform exercise tests using an exercise bike, receive two MRI scans, and complete tests of thinking skills and questionnaires.
The Effects of Effort on Fatigue and Brain Activity in TBI
This study examines how patterns of brain activity relate to cognitive fatigue, which is a feeling of exhaustion and inability to perform thinking-related activities.
MRI Studies on Multiple Sclerosis
Establishing a Clearer Measure of Mental Fatigue in Multiple Sclerosis
This study examines mental fatigue that is regularly experienced by people with multiple sclerosis. Researchers will examine levels of mental fatigue by looking at brain activation during an MRI scan and analyzing self-reported mental fatigue provided during study participation.
Memory and Learning Rehabilitation Combined with Exercise Training in Multiple Sclerosis
This study compares the effect of a combined cognitive rehabilitation and exercise approach on new learning and memory in people with multiple sclerosis and mobility disability.
Using fMRI to Study Cognitive Fatigue in MS (with Ocrevus®)
Study investigates the effect of disease-modifying medications, specifically Ocrevus® on cognitive fatigue in multiple sclerosis. Cognitive fatigue is the kind of fatigue that occurs after intense mental concentration, such as after a session of problem-solving.
MRI Studies on Neuropsychology
Changes in the Brain Associated with Character Identification
This study investigates changes in the brain that occur when people reflect on their own positive personality traits. Researchers use MRI to evaluate changes in the brain (no injections or contrast dyes are used).
A Systematized Approach to Improve Memory in Older Adults
This study investigates the effectiveness of a memory enhancement technique in adults 60 years and older. Participants are randomly assigned to either an active control group or treatment group. Both groups complete memory exercises.
MRI Studies on Spinal Cord Injury
Epidural Spinal Cord Stimulation: Addressing Spasticity and Motor Function
This study aims to expand the knowledge and capacity for neuromodulation to improve the debilitating effects of severe spasticity (spasms, tonic muscle activity and/or clonus) in persons with spinal cord injury.
Effects of Epidural Stimulation in People with Acute Spinal Cord Injury
This study evaluates the effects of epidural stimulation of the spinal cord and task-specific training on motor control, cardiovascular and respiratory functions, bowel, bladder, and sexual function in individuals with spinal cord injury.
Targeted Epidural Stimulation for Recovery of Nervous System Function, Movement, and Standing after Severe SCI
This study evaluates the effects of epidural stimulation of the spinal cord on cardiovascular (blood pressure regulation) function, voluntary movement of the legs and trunk, and standing/weight bearing in individuals with spinal cord injury.
Nerve Stimulation for Upper Extremity Recovery in Chronic Cervical Spinal Cord Injury
Study seeks to understand how the combination of upper extremity activity-based recovery training and targeted spinal cord transcutaneous (through the skin) stimulation can improve participants’ ability to use their hand, arms, and trunk.
Brain Activity in People with Chronic Neuropathic Pain and SCI
The purpose of this research study is to learn more about how patterns of brain activity change during different thinking tasks and how these changes relate to the intensity and unpleasantness of the neuropathic pain experienced.
MRI Studies on Stroke
Exercise and Reading Therapy After Stroke
This study tests the effectiveness of reading therapy combined with exercise (stationary bike cycling or stretching) for people who have difficulty reading after a left-brain stroke.
Rehab of Stroke Reading Deficits Using fMRI Neurofeedback
The purpose of this study is to investigate how reading can be improved after a left-brain stroke. The findings of this study may help to develop new methods for diagnosis and treatment of reading problems after stroke.
Reading Impairments Following Left-Sided Stroke
The goal of this research study is to better understand the brain mechanisms involved in reading. The findings from this study may help develop new methods for diagnosis and treatment of reading problems after stroke.
MRI Studies on Traumatic Brain Injury
Examining Cognitive and Physical Fatigue in Traumatic Brain Injury
This study examines brain and behavioral changes during thinking and physical tasks in individuals with traumatic brain injury. Participants perform exercise tests using an exercise bike, receive two MRI scans, and complete tests of thinking skills and questionnaires.
The Effects of Effort on Fatigue and Brain Activity in TBI
This study examines how patterns of brain activity relate to cognitive fatigue, which is a feeling of exhaustion and inability to perform thinking-related activities.
Applying Exercise to Improve Memory in TBI
This study compares the effects of two, 12-week exercise programs (aerobic cycling or stretching-and-toning) combined with memory retraining on cognitive (thinking) performance in people with traumatic brain injury.
Improving New Learning and Memory in People with Mild Cognitive Impairment
Study will administer the Kessler Foundation modified Story Memory Technique®(KF-mSMT) to individuals with mild cognitive impairment to treat impaired new learning and memory.
Comparison of Two Different Group Wellness Programs for People with TBI and their Support Persons
This study compares the effect of two different types of group wellness treatments for individuals with moderate or severe traumatic brain injury and their support persons.
Feedback and Learning in Individuals with Clinical Depression and TBI
The purpose of this research study is to examine the influence of 'feedback timing' (feedback about your performance is either presented immediately or after a delay) on learning and brain function in individuals with moderate to severe TBI with or without depression. Participants complete questionnaires and learning tasks on a computer and while in an MRI scanner.
