Volunteers are typically compensated for their time. We may be able to assist with transportation, or travel to your home. Please speak with our Research Recruitment Specialist for more information.
Below are the studies recruiting participants with MS. You can also download a flyer of all current studies here. This listing was last updated on 10/4/2018.
Investigating Cognitive Fatigue and Brain Iron Disposition in Basal Ganglia in Multiple Sclerosis
The purpose of this research study is to detect any accumulation of iron in certain regions of the brain using MRI and use this imaging data to examine the relationship between iron deposition and the severity of cognitive fatigue in MS. Cognitive fatigue is described as mental exhaustion that interferes with thinking, memory, and problem-solving.
- If you participate, you'll complete an MRI scan that will last about 1.5 hours. During part of the scan, participants will perform a study task by pressing buttons on a response box after seeing images on a screen. After the scan, participants will complete paper-and-pencil tests of thinking skills and questionnaires about everyday life, etc. This will take approximately 30 minutes.
- To qualify, volunteers must be aged 30-65 years, diagnosed with relapsing-remitting MS (RRMS), and be able to walk without an assistive device.
Emotional Processing Intervention in MS
This study examines the effects of an emotional processing training program in persons with MS.
- If you participate, you’ll complete baseline and short-term follow-up testing (thinking and emotional processing skills, 3-4 hours each) and participate in a computer-based intervention (2 sessions a week for 6 weeks, 1 hour each session).
- To qualify, volunteers must be between 18 and 65, have no neurological illness other than MS, and have no psychiatric conditions or significant history of alcohol or drug abuse.
Feedback Presentation and Learning in MS
This study examines how feedback (assessments of task performance) interact with learning in MS.
- If you participate, you’ll complete tests of your thinking skills (3 hours), then a task during an MRI scan (1 hour).
- To qualify, volunteers must be between 18 and 55 and have a diagnosis of Relapsing-Remitting MS.
Speed of Processing Training to Improve Cognition in MS
This study examines a technique to improve information processing in people with MS.
- If you participate, you’ll complete 2-3 hour tests of your thinking skills (baseline, and short-term and long-term follow up) and participate in a computer-based intervention (2 one-hour sessions a week, 5 weeks). There are optional MRI scans at baseline and follow-up testing.
- To qualify, volunteers must be between 18 and 59 and have no neurological illness other than MS.
Keeping an Eye on the Symbol Digit Modalities Test
This study examines the relationship between eye movements and speed at which you process information.
- If you participate, you’ll complete a 30 minute screening evaluation to determine eligibility. If you qualify, you will complete tasks using visual stimuli while researchers record your eye movements with a high speed camera (nothing touches your eyes) and complete tests of thinking skills (approximately 3 hours).
- To qualify, volunteers must be 30-65 years of age and have no neurological illness other than MS
Comprehensive Model of Adherence in MS
The purpose of this study is to investigate how individuals with MS make decisions regarding their MS medications and treatment.
- If you participate, you’ll complete an online survey lasting approximately 1.5-2 hours.
- To qualify, volunteers must be 18 years or older, diagnosed with Relapsing-Remitting MS, and have been recommended a disease modifying treatment (DMT) and either never initiated treatment, discontinued treatment, or presently take a recommended DMT.
Cognitive Rehabilitation and Physical Exercise in Individuals with Progressive MS
This study examines the effectiveness of thinking exercises on a computer combined with physical exercise as a treatment for difficulties with thinking, memory, and problem-solving in individuals with Progressive MS.
- Participation lasts a total of 9 months. Participants will complete initial baseline testing of thinking skills, physical fitness, and an optional fMRI scan. Participants are then randomly assigned to one of two exercise training groups that meet twice a week for 12 weeks and complete short-term and long-term follow-up testing.
- To qualify, volunteers must be 25-60 years of age, have a diagnosis of primary or secondary progressive MS, and no history of neurological disease other than MS.
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